Find a protein using PDB explorer- describe your protein, including what disease state or other real-world application it has.

The protein I chose to look at in class was 1N5O. It is related to Breast cancer and is critical for BRCA1 tumore suppressor function. It is also involved with how BRTC mutations affect BRCA1 function. This is a rather small and sinple protein in comparison to others that were seen in class. Its secondary structure consisted of 6 alpha-helix (displayed as green crayons) and 8 beta-pleated sheets (displayed as tan flat sheets). There was no quaternary structure because there were no subunits within the protein. Viewing the protein in the "backbone" mode shows the backbone of the protein with no R groups. The "all atoms" mode shows the entire protein including the R groups.

Using the online technology that we learned about in class, we would be able to determine if any amino acid sequence is already part of a currently known protein or what other known proteins come close to the sequence. Looking at similar proteins, we may also be able to relate the function of a new amino acid sequence to one very similar to it.